Here’s what’s promising. The ultimate onslaught within the war from the Aids will come with shortening your window Period or even the latent– deceitful duration of the condition- when even ve seems -ve.
Stimulating Maximal Antibody Response Tube – SMARTube — an easy, yet revolutionary breakthrough in medical technology while being imported the very first time in India may end up being the best weapon for early warning and recognition of Aids & HCV infections in people, several weeks before every other known test or diagnostic method.
Based on Dr N K Gupta-an worldwide reputed NRI physician, vascular biologist, motivational speaker and President, Society for Medicare – an India based Ngo in the area of medical education, awareness and capacity building in order to save human lives, Smartube won’t revolutionise the recognition of Aids and HCV in India but in addition helps in preserving countless lives.
“It might be the Smart Solution or Smart Weapon India must protect against the smart invaders — the lethal Aids & HCV virus who’re masters in the skill of camouflage, deceptiveness and hidden combat after quietly crippling the defenders – in the body”, states Dr Gupta.
Truly with near to between 2.four to five.seven million Aids ve people & 165,000 reported AIDS cases — 4,000,000 Men, 1,600,000 Women & 1,20,000 children — already coping with Aids, additionally to Hepatitis C virus (HCV) which makes up about one-4th of installments of chronic liver disease causing 1.5 -two million deaths in Indian Homes– INDIA can’t be left subject to Aids/AIDS – HCV.
The risks for this reason are fairly apparent as some 550,000 Aids patients have previously developed AIDS and the other 300,000 annually will build up AIDS within the next 15-twenty years. Also according to World Bank estimates India already has two million children – the biggest number AIDS orphans on the planet-who’re likely to double in next 5 years.
The neatest area of the story is the fact that SMARTube not just ensures earlier, better and finish recognition of Aids/HCV only a week after exposure but additionally enables the recognition of individuals patients who have been who have been infected, but otherwise might might have gone undetected at this testing time. By doing this SMARTube promises to become a economical way in which boosts the SENSITIVITY and SPECIFICITY of other known Aids & HCV recognition tests-with hardly any additional training or cost input.
Based on the Cdc (CDC) greater than 25% of Aids ve individuals USA are not aware of the Aids status. Healthy to look at and feeling fine– they don’t receive good care and unknowingly pass the Aids virus to other people. The popularity worldwide, including India is the fact that so many people are blissfully not aware of the Aids- HCV ve status and continue infect others while leading normal lives due to the fact-
o They have no visible or apparent signs and symptoms of Aids/AIDS – HCV
o They never felt the necessity to get tested
o It isn’t a fashionable that people get Aids – HCV tests done, even when a lifetime
o Stigma that come with taking a Aids test (what’s going to people say!), unless of course inevitable
Even otherwise, under one percent population asia get themseleves tested for Aids-HCV even once within the lifetime and worst still up to 27 % Aids infected people remain undiagnosed.
As things stand today, if an individual tests negative for Aids or HCV – it does not imply that he/she isn’t infected. On the other hand he/she may be within the most contagious stage from the infection. Such one could well infect as much as 50 -100 others before really testing positive – several weeks later. It’s because the “Window Period”.
To know how this window period affects us… we must first know how the body reacts to infections and virus attacks … For instance the body consists of in regards to a 100 million cells. Only one teaspoon of bloodstream contains about 25 billion red bloodstream cells. The defense mechanisms may be the body’s primary line defender against infection and illness. It recognizes your body’s cells and attempts to eliminate anything unfamiliar. It destroys parasites and germs – bacteria and infections but could sometimes create problems by attacking unmatched bloodstream or organs donated by someone else.
In situation on most infections, the defense mechanisms sees the foreign invaders and starts producing antibodies against them. Usually it requires 5-seven days for that antibodies to build up following the infection. Antibodies help in discovering any infection within the bloodstream, prior to the liver or lung area may take a hit.
An enormous army of defender cells containing 1000 million various kinds of white-colored bloodstream cells are created within the bone marrow every single day. A few of these cells, known as macrophages, constantly patrol your body, destroying germs every time they enter. This is actually the ‘natural’ or inborn immunity. But when contamination starts to take hold, your body fights back with much more effective T- and B-cells that provide us acquired immunity, so the germ can’t make us ill again.
However, with Aids and HCV, probably the most devastating and chronic infection–it might take days or as much as many several weeks to determine any antibodies within the bloodstream. AIDS is because the hiv (Aids), which attacks the defense mechanisms, disarming your body’s defenses against infections and cancers. Consequently even germs that create minor illnesses in healthy people could make individuals with AIDS very ill.
AIDS is really a medical problem. People develop AIDS because Aids has broken their natureal defenses against disease. Aids means the Hiv. It’s a virus that infects cells that comprise the body and replicates i.e. makes new copies of itself within individuals cells. Aids could be passed in one person to a different through connection with your body fluids of the Aids infected or Aids person. The only real reliable method to tell whether someone has Aids is thru bloodstream tests, which could identify the problem — a couple of days following the virus first joined your body.
Like several infections, Aids cannot grow or reproduce by itself. To make new copies of itself it has to infect cells of the living organism. As time passes Aids ve persons can become ill increasingly more frequently. Many years following the infection, the amount of defense mechanisms cells left in your body drops below a certain point. At this time you might be stated to possess progressed from Aids to AIDS. Generally if somebody has a number of these infections along with a low quantity of T cells, they’re stated to become struggling with AIDS. Different countries have different parameters for defining happens where a Aids ve individual is stated to possess AIDS.
Different infections attack different areas of the body – some attack your skin, others the lung area…even common cold is because the herpes virus. Why is Aids –harmful is it attacks the defense mechanisms particularly a unique kind of defense mechanisms cell referred to as a CD4 lymphocyte- that normally will get eliminate the infections. Aids is a great virus that methods and evades your body’s defenses. When the Aids virus begins, the defense mechanisms can’t ever fully eliminate it.
The majority of the Aids -HCV detction tests currently available such as the Elisa including rapid tests and residential test kits- rely on discovering the level of antibodies within the bloodstream rather from the virus itself. In situation of both Aids and HCV it will take days or several weeks after infection before antibodies against are created and detected. This infected yet serum-negative period is known as the “window period”. This can be a period when even Aids – HCV infected individuals will be looked at non-infected since they haven’t yet created or developed detectable amounts of antibodies within their bloodstream.
As lengthy because there are no antibodies, these people are diagnosed as non-infected. This really is known as your window period – time between infection and also the recognition of antibodies– this is where Smartube is available in.
Your window duration of Aids and HCV infection is really a major concern for that governments, health government bodies and professionals, bloodstream banks, vaccine and drug developers around the globe, as numerous infected individuals test negative for Aids or HCV antibodies, and therefore are thus misdiagnosed. Shortening your window period really supports the answer to saving countless lives, vast amounts of dollars, untold human sources, suffering, and deaths.
An easy process, known as Stimmunology, for stimulating the antibody production in-vitro within the bloodstream sample, just before testing it for Aids (and/or HCV) antibodies, continues to be developed, to resolve your window period. It has been implemented within the SMARTube Aids & HCV, which helps the recognition of Aids and HCV infections (throughout the window period) by overcoming, in vitro, the particular immune suppression exerted through the virus, and the reason for your window period.